AKOS B029556

AKOS B029556 - Names and Identifiers

Name	5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde
Synonyms	AKOS B029556 BUTTPARK 4618-83 TIMTEC-BB SBB000527 5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carbaldehyde 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXALDEHYDE 5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxaldehyde 5-chloro-1-methyl-3-(trifluoromethyl)-4-pyrazolecarboxaldehyde 5-Chloro-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxyaldehyde 5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBALDEHYDE
CAS	128455-62-9
EINECS	672-009-3
InChI	InChI=1/C6H4ClF3N2O/c1-12-5(7)3(2-13)4(11-12)6(8,9)10/h2H,1H3

AKOS B029556 - Physico-chemical Properties

Molecular Formula	C6H4ClF3N2O
Molar Mass	212.56
Density	1.56±0.1 g/cm3(Predicted)
Melting Point	42-44°C
Boling Point	239.6±40.0 °C(Predicted)
Flash Point	98.7°C
Vapor Presure	0.0396mmHg at 25°C
pKa	-4.03±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.501

AKOS B029556 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection

AKOS B029556 - Introduction

5-Chloro-1-methyl-3-(trifluoromethyl) pyrazole-4-carbaldehyde is an organic compound with the formula C7H4ClF3N2O. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to light yellow solid.
-Melting point: approximately 92-100°C.
-Boiling point: about 280-281°C.
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide.
-Stability: relatively stable under normal storage and operating conditions.

Use:
-It is an important organic synthesis intermediate that can be used to synthesize other organic compounds.
-Because it has chlorine, methyl and trifluoromethyl groups, it is often used as a starting material for the synthesis of drugs and pesticides in the field of medicinal chemistry and pesticide chemistry.
-It can also be used in the synthesis of dyes, paints and other organic materials.

Preparation Method:
The preparation method of 5-chloro-1-methyl-3-(trifluoromethyl) pyrazole-4-carbaldehyde can be carried out by the following steps:
1.3-bromo -5-chloropyrazole and trifluoromethyl chloride are first reacted to give 3-(trifluoromethyl)-5-chloropyrazole.
2.3-(trifluoromethyl)-5-chloropyrazole reacts with formaldehyde under alkaline conditions to give 5-chloro -1-methyl -3-(trifluoromethyl) pyrazole -4-carbaldehyde.

Safety Information:
- 5-Chloro -1-methyl -3-(trifluoromethyl) pyrazole-4-formaldehyde should be operated in a well-ventilated place to avoid inhaling its steam or dust.
-Wear appropriate protective gloves, glasses and protective clothing when using.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water. If discomfort occurs, seek medical treatment.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.

Last Update：2024-04-09 02:00:41